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Each formulation is unique, just as each drug candidate is unique. At Pharmatek, formulation projects start with a strategic formulation plan. The formulation strategy is the result of a thorough analysis of the preformulation data report, the intended manufacturing process, any patient compliance issues and the strategic goals of the company.
At Pharmatek, the comprehensive evaluation of drug candidates during pre-formulation is critical to the formulation development process. Certain candidates present specific challenges such as low bioavailability, poor solubility and/or permeability and poor physical stability. Formulation development can be helpful in overcoming many of these issues.
Execution of the formulation strategy utilizes a logical, data driven approach:
- Pre-formulation solubility and stability evaluations
- Comprehensive excipient screening
- Prototype development
- Formulation optimization and finalization
- Supporting documentation and data package
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Formulation development is often seen as a black box. At Pharmatek, it's a science. Our logical, data-driven approach to formulation development gives your compound the best chance at success and provides our clients the most efficient, straightforward process for manufacturing their compound. |
